Cystic fibrosis is a common inherited condition, particularly affecting people from a northern European background. It's caused by various mutations of the Cystic Fibrosis Transmembrane Conductance Regulator gene, shortened to "CFTR". A new Cochrane Review from August 2018 examines a class of drug that aims to correct the basic defect for people with CF with a specific mutation, and we asked lead author, Kevin Southern from the University of Liverpool in the UK, to tell us what they found.
There are concerns across the world about the rising incidence of type 2 diabetes, increasing the importance of evidence for effective ways to prevent this condition. In a December 2017 update to the Cochrane Review, Bianca Hemmingsen from Herlev University Hospital in Denmark and colleagues have summarized the latest evidence on the effects of diet and physical activity for people with intermediate hyperglycaemia or prediabetes. We asked Bianca to tell us what they found in this podcast.
The Cochrane Drugs and Alcohol Group specialises in reviews that assess, among other things, ways to reduce hazardous or harmful drinking of alcohol. One of these reviews looks at the evidence on practitioner-delivered brief interventions and we asked one of the authors, Fiona Beyer from Newcastle University in the UK to tell us about the findings from the update in February 2018.
As you can imagine, placing a breathing tube into a newborn baby is a particularly challenging task, and research has been done into different ways to do this. In May 2018, Mohan Pammi and Krithika Lingappan from Baylor College of Medicine in Houston in the USA updated the Cochrane review on comparing videolaryngoscopy to the traditional direct laryngoscopy approach and they describe the latest findings in this podcast, starting with Mohan.
The Cochrane Gynaecology and Fertility Group has prepared more than 200 reviews and in May 2018, a team from Germany, The Netherlands and New Zealand updated one of these reviews, looking at the use of letrozole for subfertile women with anovulatory polycystic ovary syndrome. Lead author, Sebastian Franik from the University of Münster in Germany describes the latest findings in this podcast.
Urinary incontinence is a distressing condition for which there are a variety of treatment options. June Cody from the Cochrane Incontinence Group and colleagues have investigated the effects of a particular type of surgery. They updated the review's findings on the effects of the operations in 2015, and published an extension in July 2017, to include more on the economic aspects. Here's June to tell us about the evidence on the clinical effects.
A variety of approaches have been suggested for reducing muscle soreness after exercise, one of which is to use antioxidant supplements. A new Cochrane Review from December 2017 brought together the evidence from the relevant research and lead author, Mayur Ranchordas from Sheffield Hallam University in the UK, tells us what they found in this podcast.
Reminiscence therapy for dementia4 Jun 2018
Coping with the increasing number of people with dementia is likely to be one of the major challenges for health systems globally in coming years and decades. There are several Cochrane Reviews of ways to treat or alleviate this condition and an updated review in March 2018 looks at the evidence for reminiscence therapy. We asked lead author, Bob Woods from Bangor University in Wales, to summarise the findings in this podcast.
Many people vomit or feel nauseous after surgery, and it’s important to find effective ways to ease these unpleasant symptoms. One of the updated Cochrane Reviews in March 2018 looks at the effect of aromatherapy and we asked Sonia Hines from the Queensland Centre for Evidence‐Based Nursing & Midwifery in Australia to tell us more about the latest results.
Selenium for preventing cancer25 May 2018
More than half a dozen Cochrane Reviews have been done in various areas of health, to examine the evidence on the potential benefits of Selenium, a naturally occurring element with both nutritional and toxicological properties. The review looking at its possible role in the prevention of cancer was updated in January 2018 and one of the authors, Maree Brinkman from the Nutrition Biomed Research Institute in Melbourne in Australia. gives us the latest findings in this podcast.
The Cochrane Pain, Palliative and Supportive Care Group has been producing Cochrane Reviews for more than 20 years, including dozens covering a wide range of therapies for pain. In April 2018, their review of brain stimulation for chronic pain was updated and lead author Neil E O'Connell from Brunel University London in the UK tells us about the latest evidence in this podcast.
The Cochrane Work Group has produced many reviews relevant to occupational health and some of these relate directly to the health of healthcare workers. In March 2018, they published a new review doing just that, examining the evidence on the handling of medicines that might be dangerous to staff. Kurinchi Selvan Gurusamy, from UCL Medical School in London England, tells us what they found.
Many women suffer from incontinence during or after pregnancy, and pelvic muscle exercises are one way to help. In an updated Cochrane Review in December 2017, Stephanie Woodley and Jean Hay-Smith from the University of Otago in New Zealand, and colleagues present the evidence from nearly 40 trials; and they tell us the findings in this podcast.
The Cochrane Pain, Palliative and Supportive Care Group is producing a series of reviews on drugs for the treatment of people with fibromyalgia. One of these, published in March 2018, examines the effects of a class of antidepressants called serotonine noradrenaline reuptake inhibitors. In this podcast, one of the co-authors, Brian Walitt, from the National Institute of Nursing Research in the USA, describes the findings.
The Cochrane Developmental, Psychosocial and Learning Problems Group covers a wide range of topics relevant to the mental health of both adults and children in the more than 140 Cochrane Reviews it has produced to date. In March 2018, it added to these with a new review of cognitive-behavioural interventions for attention deficit hyperactivity disorder in adults. We asked one of the authors, Pablo Lopez from INECO Foundation and Favaloro University in Buenos Aires, Argentina, to tell us more in this podcast.
Cochrane Diagnostic Test Accuracy reviews bring together the evidence that should help practitioners to choose the most appropriate way to diagnose an illness or condition. This is now the case for the stomach bug, Helicobacter pylori, and we asked Lawrence Best from the UCL Medical School in London England to tell us about the findings of this March 2018 review.
As well as the problems with blood sugar control that are caused by diabetes, the condition can lead to a variety of other problems. One of these is an eye problem called diabetic retinopathy and it’s important that people with diabetes are checked for this. A January 2018 Cochrane Review looks at how to increase attendance at these screening visits and lead author, John Lawrenson from the City University of London in the UK, tells us more in this podcast.
Heart attack and stroke are the most common causes of death, illness, disability and reduced quality of life in industrialised countries, and several Cochrane Reviews look at ways to prevent these cardiovascular events. A new review from June 2017 looks at the evidence for a B-vitamin called niacin. One of the reviews' authors, Matthias Briel from Basel Institute for Clinical Epidemiology and Biostatistics in Switzerland, outlines the findings in this podcast.
The Cochrane Tobacco Addiction Group has produced dozens of reviews of the effects of a wide variety of interventions to help smokers quit. The reviews are updated periodically to incorporate new evidence and the second update of the review focusing on interventions for young people was published in November 2017. Lead author, Tom Fanshawe from the Nuffield Department of Primary Care Health Sciences in the University of Oxford in the UK bring us up to date with the findings.
The Cochrane Drugs and Alcohol Group has produced several reviews of the effects of interventions intended to reduce heavy drinking. The collection was extended in September 2017 with an investigation of the use a computer to provide personalised advice. We asked one of the authors, Fiona Beyer from Newcastle University in the UK, to tell us what they found.
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