Where private research funders stow their cash and studying gun deaths in children
6 Dec 2018
A new Science investigation reveals several major private research funders—including the Wellcome Trust and the Robert Wood Johnson Foundation—are making secretive offshore investments at odds with their organizational missions. Host Meagan Cantwell talks with writer Charles Piller about his deep dive into why some private funders choose to invest in these accounts. In the United States, gun injuries kill more children annually than pediatric cancer, but funding for firearm research pales in comparison. On this week’s show, host Sarah Crespi talks with Staff Writer Meredith Wadman and emergency physician Rebecca Cunningham about how a new grant will jump-start research on gun deaths in children. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast [Image: Bernard Spragg; Music: Jeffrey Cook]
The universe’s star formation history and a powerful new helper for evolution29 Nov 2018
In a fast-changing environment, evolution can be slow—sometimes so slow that an organism dies out before the right mutation comes along. Host Sarah Crespi speaks with Staff Writer Elizabeth Pennisi about how plastic traits—traits that can alter in response to environmental conditions—could help life catch up. Also on this week’s show, host Meagan Cantwell talks with Marco Ajello a professor of physics and astronomy at Clemson University in South Carolina about his team’s method to determine the universe’s star formation history. By looking at 739 blazars, supermassive black holes at the center of galaxies, Ajello and his team were able to model the history of stars since the big bang. Finally, in this month’s book segment, Jen Golbeck interviews Christine Du Bois about her book Story of Soy. You can listen to more book segments and read more reviews on our books blog, Books et al. This week’s episode was edited by Podigy. Read a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: NASA/Goddard Space Flight Center Conceptual Image Lab; Music: Jeffrey Cook]
Exploding the Cambrian and building a DNA database for forensics22 Nov 2018
First, we hear from science writer Joshua Sokol about his trip to the Cambrian—well not quite. He talks with host Megan Cantwell about his travels to a remote site in the mountains of British Columbia where some of Earth’s first animals—including a mysterious, alien-looking creature—are spilling out of Canadian rocks. Also on this week’s show, host Sarah Crespi talks with James Hazel a postdoctoral research fellow at the Center for Genetic Privacy and Identity in Community Settings at Vanderbilt University in Nashville about a proposal for creating a universal forensic DNA database. He and his co-authors argue that current, invasive practices such as law enforcement subpoenaing medical records, commercial genetic profiles, and other sets of extremely detailed genetic information during criminal investigations, would be curtailed if a forensics-use-only universal database were created. This week’s episode was edited by Podigy. Read a transcript (PDF) Listen to previous podcasts. About the Science Podcast
The worst year ever and the effects of fasting15 Nov 2018
When was the worst year to be alive? Contributing Correspondent Ann Gibbons talks to host Sarah Crespi about a contender year that features a volcanic eruption, extended darkness, cold summer, and a plague. Also on this week’s show, host Meagan Cantwell talks with Andrea Di Francesco of the National Institutes of Health’s National Institute on Aging in Baltimore, Maryland, about his review of current wisdom on fasting and metabolism. Should we start fasting—if not to extend our lives maybe to at least to give ourselves a healthy old age? In a special segment from our policy desk, Deputy Editor David Malakoff discusses the results of the recent U.S. election with Senior Correspondent Jeffrey Mervis and we learn what happened to the many scientist candidates that ran and some implications for science policy. This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Photo: Scott Suchman; Styling: Nichole Bryant; Music: Jeffrey Cook]
A big increase in monkey research and an overhaul for the metric system8 Nov 2018
A new report suggests a big increase in the use of monkeys in laboratory experiments in the United States in 2017. Online News Editor David Grimm joins host Sarah Crespi to discuss which areas of research are experiencing this rise and the possible reasons behind it. Also this week, host Meagan Cantwell talks with staff writer Adrian Cho about a final push to affix the metric system’s measures to physical constants instead of physical objects. That means the perfectly formed 1-kilogram cylinder known as Le Grand K is no more; it also means that the meter, the ampere, and other units of measure are now derived using complex calculations and experiments. This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Peter Nijenhuis/Flickr; Music: Jeffrey Cook]
How the appendix could hold the keys to Parkinson’s disease, and materials scientists mimic nature1 Nov 2018
For a long time, Parkinson’s disease was thought to be merely a disorder of the nervous system. But in the past decade researchers have started to look elsewhere in the body for clues to this debilitating disease—particularly in the gut. Host Meagan Cantwell talks with Viviane Labrie of the Van Andel Institute in Grand Rapids, Michigan, about new research suggesting people without their appendixes have a reduced risk of Parkinson’s. Labrie also describes the possible mechanism behind this connection. And host Sarah Crespi talks with Peter Fratzl of the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany, about what materials scientists can learn from nature. The natural world might not produce innovations like carbon nanotubes, but evolution has forged innumerable materials from very limited resources—mostly sugars, proteins, and minerals. Fratzl discusses how plants make time-release seedpods that are triggered by nothing but fire and rain, the amazing suckerin protein that comprises squid teeth, and how cicadas make their transparent, self-cleaning wings from simple building blocks. Fratzl’s review is part of a special section in Science on composite materials. Read the whole package, including a review on using renewables like coconut fiber for building cars and incorporating carbon nanotubes and graphene into composites. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Roger Smith/Flickr; Music: Jeffrey Cook]
Children sue the U.S. government over climate change, and how mice inherit their gut microbes25 Oct 2018
A group of children is suing the U.S. government—claiming their rights to life, liberty, and property are under threat from climate change thanks to government policies that have encouraged the use and extraction of fossil fuels. Host Meagan Cantwell interviews news writer Julia Rosen on the ins and outs of the suit and what it could mean if the kids win the day. Also this week, host Sarah Crespi talks with Andrew Moeller of Cornell University about his work tracing the gut microbes inherited through 10 generations of mice. It turns out the fidelity is quite high—you can still tell mice lineages apart by their gut microbes after 10 generations. And horizontally transmitted microbes, those that jump from one mouse line to another through exposure to common spaces or handlers, were more likely than inherited bacteria to be pathogenic and were often linked to illnesses in people. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Bob Dass/Flickr; Music: Jeffrey Cook]
Mutant cells in the esophagus, and protecting farmers from dangerous pesticide exposure18 Oct 2018
As you age, your cells divide over and over again, leading to minute changes in their genomes. New research reveals that in the lining of the esophagus, mutant cells run rampant, fighting for dominance over normal cells. But they do this without causing any detectable damage or cancer. Host Sarah Crespi talks to Phil Jones, a professor of cancer development at the University of Cambridge in the United Kingdom, about what these genome changes can tell us about aging and cancer, and how some of the mutations might be good for you. Most Western farmers apply their pesticides using drones and machinery, but in less developed countries, organophosphate pesticides are applied by hand, resulting in myriad health issues from direct exposure to these neurotoxic chemicals. Host Meagan Cantwell speaks with Praveen Vemula, a research investigator at the Institute for Stem Cell Biology and Regenerative Medicine in Bengaluru, India, about his latest solution—a cost-effective gel that can be applied to the skin to limit pesticide-related toxicity and mortality. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image:Navid Folpour/Flickr; Music: Jeffrey Cook]
A small isolated town in Colombia is home to a large cluster of people with fragile X syndrome—a genetic disorder that leads to intellectual disability, physical abnormalities, and sometimes autism. Spectrum staff reporter Hannah Furfaro joins host Sarah Crespi to discuss the history of fragile X in the town of Ricaurte and the future of the people who live there. Also this week, we talk about greening up grass. Lawns of green grass pervade urban areas all around the world, regardless of climate, but the cost of maintaining them may outweigh their benefits. Host Meagan Cantwell talks with Maria Ignatieva of The University of Western Australia in Perth and the Swedish University of Agricultural Sciences in Uppsala about how lawns can be transformed to contribute to a more sustainable future. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Adam Kerfoot-Roberts/Flickr; Music: Jeffrey Cook]
Hoping to spot subatomic particles called neutrinos smashing into Earth, the balloon-borne Antarctic Impulsive Transient Antenna (ANITA) detector has circled the South Pole four times. ANITA has yet to detect those particles, but it has twice seen oddball radio signals that could be evidence of something even weirder: some heavier particle unknown to physicists’ standard model, burrowing up through Earth. Science writer Adrian Cho joins host Sarah Crespi to discuss the possibility that this reading could lead to a big change in physics. Next, host Meagan Cantwell asks researcher Ben Dalziel what makes a bad—or good—flu year. Traditionally, research has focused on two factors: climate, which impacts how long the virus stays active after a sneeze or cough, and changes in the virus itself, which can influence its infectiousness. But these factors don’t explain every pattern. Dalziel, a population biologist in the Departments of Integrative Biology and Mathematics at Oregon State University in Corvallis, explains how humidity and community size shape the way influenza spreads. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Stuart Rankin/Flickr; Music: Jeffrey Cook]
The future of PCB-laden orca whales, and doing genomics work with Indigenous people27 Sep 2018
Science has often treated Indigenous people as resources for research—especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to start a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are still in the environment—in soil and air—and in animal tissues, particularly those of killer whales. These toxic compounds start out at minute levels in tiny organisms, but as the small are eaten by the slightly larger, the PCB concentration increases—from plankton, to fish, to seals—until you are at killer whales with PCB-packed blubber. Ailsa Hall, director of the Sea Mammal Research Unit at St. Andrews University in the United Kingdom, talks with host Sarah Crespi about her group’s work measuring PCB levels in different killer whale populations and calculating the effect of PCBs on those populations 100 years from now. In this month’s book segment, Jen Golbeck interviews Damon Centola about his book How Behavior Spreads: The Science of Complex Contagions. You can listen to more books segment and read more reviews on our books blog, Books et al. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts About the Science Podcast [Image: Public domain; Music: Jeffrey Cook]
Metaresearchers take on meta-analyses, and hoary old myths about science20 Sep 2018
Meta-analyses—structured analyses of many studies on the same topic—were once seen as objective and definitive projects that helped sort out conflicts amongst smaller studies. These days, thousands of meta-analyses are published every year—many either redundant or contrary to earlier metaworks. Host Sarah Crespi talks to freelance science journalist Jop de Vrieze about ongoing meta-analysis wars in which opposing research teams churn out conflicting metastudies around important public health questions such as links between violent video games and school shootings and the effects of antidepressants. They also talk about what clues to look for when trying to evaluate the quality of a meta-analysis. Sarah also talked with three other contributors to our “Research on Research” special issue. Pierre Azoulay of the Massachusetts Institute of Technology (MIT) in Cambridge, Ben Jones of Northwestern University in Evanston, Illinois, and MIT’s Heidi Williams discuss the evidence for some hoary old scientific home truths. See whether you can guess who originally made these claims and how right or wrong they were: Do scientists make great contributions after age 30? How important is it to stand on the shoulders of giants? Does the truth win, or do its opponents just eventually die out? Read the rest of the package on science under scrutiny here. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Davide Bonazzi/@SalzmanArt; Show music: Jeffrey Cook; additional music: Nguyen Khoi Nguyen]
The youngest sex chromosomes on the block, and how to test a Zika vaccine without Zika cases13 Sep 2018
Strawberries had both male and female parts, like most plants, until several million years ago. This may seem like a long time ago, but it actually means strawberries have some of the youngest sex chromosomes around. What are the advantages of splitting a species into two sexes? Host Sarah Crespi interviews freelance journalist Carol Cruzan Morton about her story on scientists’ journey to understanding the strawberry’s sexual awakening. In 2016, experimental Zika vaccines were swiftly developed in response to the emergence of serious birth defects in the babies of infected woman. Two years after the height of Zika cases, there’s so little spread of the virus in the Americas that it has stymied vaccine trials. Researchers hope to overcome this hurdle with “human challenge experiments”—vaccinating people, then intentionally infecting them with Zika to see whether they’re protected from the virus. Meagan Cantwell talks with staff writer Jon Cohen about his news story that highlights the risks and rewards of human challenge experiments. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Public domain; Music: Jeffrey Cook]
We are in the middle of what some scientists are calling the sixth mass extinction and not all at-risk species can be saved. That’s causing some conservationists to say we need to start thinking about “species triage.” Meagan Cantwell interviews freelance journalist Warren Cornwall about his story on weighing the costs of saving Canada’s endangered caribou and the debate among conservationists on new approaches to conservation. And host Sarah Crespi interviews Hope Michelsen, a staff scientist at Sandia National Laboratories in Livermore, California, about mysterious origins of soot. The black dust has been around since fire itself, but researchers never knew how the high-energy environment of a flame can produce it—until now. Michelsen walks Sarah through the radical chemistry of soot formation—including its formation of free radicals—and discusses soot’s many roles in industry, the environment, and even interstellar space. Check out this useful graphic describing the soot inception process in the related commentary article. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Darren Bertram/Flickr; Music: Jeffrey Cook]
A new project out of the Center for Open Science in Charlottesville, Virginia, found that of all the experimental social science papers published in Science and Nature from 2010–15, 62% successfully replicated, even when larger sample sizes were used. What does this say about peer review? Host Sarah Crespi talks with Staff Writer Kelly Servick about how this project stacks up against similar replication efforts, and whether we can achieve similar results by merely asking people to guess whether a study can be replicated. Podcast producer Meagan Cantwell interviews Emily Brodsky of the University of California, Santa Cruz, about her research report examining why earthquakes occur as far as 10 kilometers from wastewater injection and fracking sites. Emily discusses why the well-established mechanism for human-induced earthquakes doesn’t explain this distance, and how these findings may influence where we place injection wells in the future. In this month’s book podcast, Jen Golbeck interviews Judea Pearl and Dana McKenzie, authors of The Book of Why: The New Science of Cause and Effect. They propose that researchers have for too long shied away from claiming causality and provide a road map for bringing cause and effect back into science. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Jens Lambert, Shutterstock; Music: Jeffrey Cook]
Sending flocks of tiny satellites out past Earth orbit and solving the irrigation efficiency paradox23 Aug 2018
Small satellites—about the size of a briefcase—have been hitching rides on rockets to lower Earth orbit for decades. Now, because of their low cost and ease of launching, governments and private companies are looking to expand the range of these “sate-lites” deeper into space. Host Sarah Crespi talks with Deputy News Editor Eric Hand about the mods and missions in store for so-called CubeSats. And our newest podcast producer Meagan Cantwell interviews Quentin Grafton of Australian National University in Canberra and Brad Udall of Colorado State University in Fort Collins about something called the “irrigation efficiency paradox.” As freshwater supplies dry up around the world, policymakers and farmers have been quick to try to make up the difference by improving irrigation, a notorious water waster. It turns out that both human behavior and the difficulty of water measurement are plaguing water conservation efforts in agriculture. For example, when farms find they are using less water, they tend to plant ever-more-water-intensive crops. Now, researchers are trying to get the message out about the behavioral component of this issue and tackle the measurement problem, using cheap remote-sensing technology, but with water scarcity looming ahead, we have to act soon. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: John A. Kelley, USDA Natural Resources Conservation Service; Music: Jeffrey Cook]
Ancient volcanic eruptions, and peer pressure—from robots16 Aug 2018
Several thousand years ago the volcano under Santorini in Greece—known as Thera—erupted in a tremendous explosion, dusting the nearby Mediterranean civilizations of Crete and Egypt in a layer of white ash. This geological marker could be used to tie together many ancient historical events, but the estimated date could be off by a century. Contributing Correspondent Lizzie Wade joins host Sarah Crespi to talk about a new study that used tree rings to calibrate radiocarbon readings—and get closer to pinning down a date. The findings also suggest that scientists may need to change their standard radiocarbon dating calibration curve. Sarah also talks to Tony Belpaeme of Ghent University in Belgium and Plymouth University in the United Kingdom about his Science Robotics paper that explored whether people are susceptible to peer pressure from robots. Using a classic psychological measure of peer influence, the team found that kids from ages 7 to 9 occasionally gave in to social pressure from robot peers, but adults did not. This week’s episode was edited by Podigy, with help from Meagan Cantwell. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Softbank Robotics; Music: Jeffrey Cook]
We now live in the Meghalayan age—the last age of the Holocene epoch. Did you get the memo? A July decision by the International Commission on Stratigraphy, which is responsible for naming geological time periods, divided the Holocene into three ages: the Greenlandian, the Northgrippian, and the Meghalayan. The one we live in—the Meghalayan age (pronounced “megalion”)—is pegged to a global drought thought to have happened some 4200 years ago. But many critics question the timing of this latest age and the global expanse of the drought. Staff writer Paul Voosen talks with host Sarah Crespi about the evidence for and against the global drought—and what it means if it’s wrong. Sarah also talks to staff writer Kelly Servick about her feature story on what happens when biocontrol goes out of control. Here’s the setup: U.S. Department of Agriculture researchers wanted to know whether brown marmorated stink bugs that have invaded the United States could be controlled—aka killed—by importing their natural predators, samurai wasps, from Asia. But before they could find out, the wasps showed up anyway. Kelly discusses how using one species to combat another can go wrong—or right—and what happens when the situation outruns regulators. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: Melissa McMasters/Flickr; Music: Jeffrey Cook]
How our brains may have evolved for language, and clues to what makes us leaders—or followers2 Aug 2018
Yes, humans are the only species with language, but how did we acquire it? New research suggests our linguistic prowess might arise from the same process that brought domesticated dogs big eyes and bonobos the power to read others’ intent. Online News Editor Catherine Matacic joins host Sarah Crespi to talk about how humans might have self-domesticated themselves, leading to physical and behavioral changes that gave us a “language-ready” brain. Sarah also talks with Micah Edelson of the University of Zurich in Switzerland about his group’s research into the role that “responsibility aversion”—the reluctance to make decisions for a group—might play when people decide to lead or defer in a group setting. In their experiments, the team found that some people adjusted how much risk they would take on, depending on whether they were deciding for themselves alone or for the entire group. The ones who didn’t—those who stuck to the same plan whether others were involved or not—tended to score higher on standardized tests of leadership and have held higher military rank. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: Scaly breasted munia/Ravi Vaidyanathan; Music: Jeffrey Cook]
Liquid water on Mars, athletic performance in transgender women, and the lost colony of Roanoke26 Jul 2018
Billions of years ago, Mars probably hosted many water features: streams, rivers, gullies, etc. But until recently, water detected on the Red Planet was either locked up in ice or flitting about as a gas in the atmosphere. Now, researchers analyzing radar data from the Mars Express mission have found evidence for an enormous salty lake under the southern polar ice cap of Mars. Daniel Clery joins host Sarah Crespi to discuss how the water was found and how it can still be liquid—despite temperatures and pressures typically inhospitable to water in its liquid form. Read the research. Sarah also talks with science journalist Katherine Kornei about her story on changing athletic performance after gender transition. The feature profiles researcher Joanna Harper on the work she has done to understand the impacts of hormone replacement therapy and testosterone levels in transgender women involved in running and other sports. It turns out within a year of beginning hormone replacement therapy, transgender women plateau at their new performance level and stay in a similar rank with respect to the top performers in the sport. Her work has influenced sports oversight bodies like the International Olympic Committee. In this month’s book segment, Jen Golbeck interviews Andrew Lawler about his book The Secret Token: Myth, Obsession, and the Search for the Lost Colony of Roanoke. Next month’s book will be The Book of Why: The New Science of Cause and Effect by Judea Pearl and Dana Mackenzie. Write us at sciencepodcast@aaas.org or tweet to us @sciencemagazine with your questions for the authors. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: Henry Howe; Music: Jeffrey Cook]
