Nigeria, Russia, and Florida seem like an odd set, but they all have one thing in common: growing caseloads of HIV. Science Staff Writer Jon Cohen joins host Sarah Crespi to talk about this week’s big read on how the fight against HIV/AIDS is evolving in these diverse locations. Sarah also talks with Armin Raznahan of the National Institute of Mental Health in Bethesda, Maryland, about his group’s work measuring which parts of the human brain are bigger in bigger brains. Adult human brains can vary as much as two times in size—and until now this expansion was thought to be evenly distributed. However, the team found that highly integrative regions are overrepresented in bigger brains, whereas regions related to processing incoming sensory information such as sight and sound tend to be underrepresented. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Misha Friedman; Music: Jeffrey Cook]
Science books for summer, and a blood test for predicting preterm birth
7 Jun 2018
What book are you taking to the beach or the field this summer? Science’s books editor Valerie Thompson and host Sarah Crespi discuss a selection of science books that will have you catching comets and swimming with the fishes. Sarah also talks with Mira Moufarrej of Stanford University in Palo Alto, California, about her team’s work on a new blood test that analyzes RNA from maternal blood to determine the gestational age of a fetus. This new approach may also help predict the risk of preterm birth. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: William Warby/Flickr; Music: Jeffrey Cook]
The first midsize black holes, and the environmental impact of global food production31 May 2018
Astronomers have been able to detect supermassive black holes and teeny-weeny black holes but the midsize ones have been elusive. Now, researchers have scanned through archives looking for middle-size galaxies and found traces of these missing middlers. Host Sarah Crespi and Staff Writer Daniel Clery discuss why they were so hard to find in the first place, and what it means for our understanding of black hole formation. Farming animals and plants for human consumption is a massive operation with a big effect on the planet. A new research project that calculated the environmental impact of global food production shows highly variable results for different foods—and for the same foods grown in different locations. Sarah talks with one of the researchers—Joseph Poore of the University of Oxford in the United Kingdom—about how understanding this diversity can help cut down food production’s environmental footprint and help consumers make better choices. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Miltos Gikas/Flickr; Music: Jeffrey Cook]
Sketching suspects with DNA, and using light to find Zika-infected mosquitoes24 May 2018
DNA fingerprinting has been used to link people to crimes for decades, by matching DNA from a crime scene to DNA extracted from a suspect. Now, investigators are using other parts of the genome—such as markers for hair and eye color—to help rule people in and out as suspects. Staff Writer Gretchen Vogel talks with Sarah Crespi about whether science supports this approach and how different countries are dealing with this new type of evidence. Sarah also talks with Jill Fernandes of the University of Queensland in Brisbane, Australia, about her Science Advances paper on a light-based technique for detecting Zika in mosquitoes. Instead of grinding up the bug and extracting Zika DNA, her group shines near-infrared light through the body. Mosquitoes carrying Zika transmit this light differently from uninfected ones. If it’s successful in larger trials, this technique could make large-scale surveillance of infected mosquitoes quicker and less expensive. In our monthly books segment, Jen Golbeck talks with author Sarah-Jayne Blakemore about her new work: Inventing Ourselves: The Secret Life of the Teenage Brain. You can check out more book reviews and share your thoughts on the Books et al. blog. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: National Institute of Allergy and Infectious Diseases, National Institutes of Health; Music: Jeffrey Cook]
Tracking ancient Rome’s rise using Greenland’s ice, and fighting fungicide resistance17 May 2018
Two thousand years ago, ancient Romans were pumping lead into the air as they smelted ores to make the silvery coin of the realm. Online News Editor David Grimm talks to Sarah Crespi about how the pollution of ice in Greenland from this process provides a detailed 1900-year record of Roman history. This week is also resistance week at Science—where researchers explore the global challenges of antibiotic resistance, pesticide resistance, herbicide resistance, and fungicide resistance. Sarah talks with Sarah Gurr of the University of Exeter in the United Kingdom about her group’s work on the spread of antifungal resistance and what it means for crops and in the clinic. And in a bonus books segment, staff writer Jennifer Couzin-Frankel talks about medicine and fraud in her review of Bad Blood: Secrets and Lies in a Silicon Valley Startup by John Carreyrou. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Wheat rust/Oregon State University; Music: Jeffrey Cook]
Who were the first horse tamers? Online News Editor Catherine Matacic talks to Sarah Crespi about a new study that brings genomics to bear on the question. The hunt for the original equine domesticators has focused on Bronze Age people living on the Eurasian steppe. Now, an ancient DNA analysis bolsters the idea that a small group of hunter-gatherers, called the Botai, were likely the first to harness horses, not the famous Yamnaya pastoralists often thought to be the originators of the Indo-European language family. Sarah also talks with News Intern Katie Langin about her feature story on a single salmon gene that may separate spring- and fall-run salmon. Conservationists, regulators, and citizens are fiercely debating the role such a small bit of DNA plays in defining distinct populations. Is the spring run distinct enough to warrant protection? This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Jessica Piispanen/USFWS; Music: Jeffrey Cook]
The twins climbing Mount Everest for science, and the fractal nature of human bone3 May 2018
To study the biological differences brought on by space travel, NASA sent one twin into space and kept another on Earth in 2015. Now, researchers from that project are trying to replicate that work planet-side to see whether the differences in gene expression were due to extreme stress or were specific to being in space. Sarah Crespi talks with Online News Editor Catherine Matacic about a “control” study using what might be a comparably stressful experience here on Earth: climbing Mount Everest. Catherine also shares a recent study that confirmed what one reddit user posted 5 years ago: A single path stretching from southern Pakistan to northeastern Russia will take you on the longest straight-line journey on Earth, via the ocean. Finally, Sarah talks with Roland Kröger of the University of York in the United Kingdom about his group’s study published this week in Science. Using a combination of techniques usually reserved for materials science, the group explored the nanoscale arrangement of mineral in bone, looking for an explanation of the tissue’s contradictory combination of toughness and hardness. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Human bone (20X) by Berkshire Community College Bioscience Image Library; Music: Jeffrey Cook]
Deciphering talking drums, and squeezing more juice out of solar panels26 Apr 2018
Researchers have found new clues to how the “talking drums” of one Amazonian tribe convey their messages. Sarah Crespi talks with Online News Editor Catherine Matacic about the role of tone and rhythm in this form of communication. Getting poked with a needle will probably get you moving. Apparently, it also gets charges moving in certain semiconductive materials. Sarah interviews Marin Alexe of The University of Warwick in Coventry, U.K., about this newfound flexo-photovoltaic effect. Alexe’s group found that prodding or denting certain semiconductors with tiny needles causes them to suddenly produce current in response to light. That discovery could enhance the efficiency of current of solar cell technologies. Finally, in our books segment, Jen Golbeck interviews Lucy Cooke about her new book The Truth About Animals: Stoned Sloths, Lovelorn Hippos, and Other Tales from the Wild Side of Wildlife. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Adam Levine/Flickr; Music: Jeffrey Cook]
Drug use in the ancient world, and what will happen to plants as carbon dioxide levels increase19 Apr 2018
Armed with new data, archaeologists are revealing that mind-altering drugs were present at the dawn of the first complex societies some 5000 years ago in the ancient Middle East. Contributing writer Andrew Lawler joins Sarah Crespi to discuss the evidence for these drugs and how they might have impacted early societies and beliefs. Sarah also interviews Sarah Hobbie of the University of Minnesota about the fate of plants under climate change. Will all that extra carbon dioxide in the air be good for certain types of flora? A 20-year long study published this week in Science suggests theoretical predictions have been off the mark. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Public domain Music: Jeffrey Cook]
How DNA is revealing Latin America’s lost histories, and how to make a molecule from just two atoms12 Apr 2018
Geneticists and anthropologists studying historical records and modern-day genomes are finding traces of previously unknown migrants to Latin America in the 16th and 17th centuries, when Asians, Africans, and Europeans first met indigenous Latin Americans. Sarah Crespi talks with contributing correspondent Lizzie Wade about what she learned on the topic at the American Association of Physical Anthropologists’s annual meeting in Austin. Sarah also interviews Kang-Keun Ni about her research using optical tweezers to bring two atoms—one cesium and one sodium—together into a single molecule. Such precise control of molecule formation is allowing new observations of these basic processes and is opening the door to creating new molecules for quantum computing. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Juan Fernando Ibarra; Music: Jeffrey Cook]
Legendary Viking crystals, and how to put an octopus to sleep5 Apr 2018
A millennium ago, Viking navigators may have used crystals known as “sunstones” to navigate between Norway and Greenland. Sarah Crespi talks with Online News Editor David Grimm about how one might use a crystal to figure out where they are. Sarah also interviews freelancer Danna Staaf about her piece on sedating cephalopods. Until recently, researchers working with octopuses and squids faced the dilemma of not knowing whether the animals were truly sedated or whether only their ability to respond had been suppressed. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Nicholas Roerich, Guests from Overseas; Music: Jeffrey Cook]
Chimpanzee retirement gains momentum, and x-ray ‘ghost images’ could cut radiation doses29 Mar 2018
Two of the world’s most famous research chimpanzees have finally retired. Hercules and Leo arrived at a chimp sanctuary in Georgia last week. Sarah Crespi checks in with Online News Editor David Grimm on the increasing momentum for research chimp retirement since the primates were labeled endangered species in 2015. Sarah also interviews freelancer Sophia Chen about her piece on x-ray ghost imaging—a technique that may lead to safer medical imaging done with cheap, single-pixel cameras. David Malakoff joins Sarah to talk about the big boost in U.S. science funding signed into law over the weekend. Finally, Jen Golbeck interviews author Stephanie Elizabeth Mohr on her book First in Fly: Drosophila Research and Biological Discovery for our monthly books segment. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Crystal Alba/Project Chimps; Music: Jeffrey Cook]
Researchers are converging on which genes are linked to morning sickness—the nausea and vomiting associated with pregnancy—and the more severe form: hyperemesis gravidarum (HG). And once we know what those genes are—can we help pregnant women feel better? News intern Roni Dengler joins Sarah Crespi to talk about a new study that suggests a protein already flagged for its role in cancer-related nausea may also be behind HG. In a second segment, Tracy Bedrosian of the Neurotechnology Innovations Translator talks about how the amount of time spent being licked by mom might be linked to changes in the genetic code of hippocampal neurons in mice pups. Could these types of genomic changes be a new type of plasticity in the brain? This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Jacob Bøtter/Flickr; Music: Jeffrey Cook]
How humans survived an ancient volcanic winter and how disgust shapes ecosystems15 Mar 2018
When Indonesia’s Mount Toba blew its top some 74,000 years ago, an apocalyptic scenario ensued: Tons of ash and debris entered the atmosphere, coating the planet in ash for 2 weeks straight and sending global temperatures plummeting. Despite the worldwide destruction, humans survived. Sarah Crespi talks with Online News Editor Catherine Matacic about how life after Toba was even possible—were humans decimated, or did they rally in the face of a suddenly extra hostile planet? Next, Julia Buck of the University of California, Santa Barbara, joins Sarah to discuss her Science commentary piece on landscapes of disgust. You may have heard of a landscape of fear—how a predator can influence an ecosystem not just by eating its prey, but also by introducing fear into the system, changing the behavior of many organisms. Buck and colleagues write about how disgust can operate in a similar way: Animals protect themselves from parasites and infection by avoiding disgusting things such as dead animals of the same species or those with disease. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Emma Forsber/Flickr; Music: Jeffrey Cook]
Did people domesticate animals? Or did they domesticate themselves? Online News Editor David Grimm talks with Sarah Crespi about a recent study that looked at self-domesticating mice. If they could go it alone, could cats or dogs have done the same in the distant past? Next, Sinan Aral of the Massachusetts Institute of Technology in Cambridge joins Sarah to discuss his work on true and false rumor cascades across all of Twitter, since its inception. He finds that false news travels further, deeper, and faster than true news, regardless of the source of the tweet, the kind of news it was, or whether bots were involved. In a bonus segment recording during a live podcasting event at the AAAS Annual Meeting in Austin, Sarah first speaks with Ben Munson of the University of Minnesota in Minneapolis about markers of gender and sexual orientation in spoken language and then Adrienne Hancock of The George Washington University in Washington, D.C., talks about using what we know about gender and communication to help transgender women change their speech and communication style. Live recordings sessions at the AAAS meeting were supported by funds from the European Commission. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Rudolf Jakkel (CC0); Music: Jeffrey Cook]
For some time after the big bang there were no stars. Researchers are now looking at cosmic dawn—the time when stars first popped into being—and are seeing hints of dark matter’s influence on supercold hydrogen clouds. News Writer Adrian Cho talks with Sarah Crespi about how this observation was made and what it means for our understanding of dark matter. Sarah also interviews Joanna Kaplanis of the Wellcome Sanger Institute in Hinxton, U.K., about constructing enormous family trees based on an online social genealogy platform. What can we learn from the biggest family tree ever built—with 13 million members spanning 11 generations? In a bonus segment recording during a live podcasting event at the AAAS Annual Meeting in Austin, Sarah talks with Michael Varnum of Arizona State University in Tempe about what people think they will do if humanity comes into contact with aliens that just happen to be microbes. Live recordings sessions at the AAAS meeting were supported by funds from the European Commission. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Kilo-Degree Survey Collaboration/H. Hildebrandt & B. Giblin/ESO; Music: Jeffrey Cook]
We talk about the techniques of painting sleuths, how to combat alternative facts or “fake news,” and using audio signposts to keep birds from flying into buildings. For this segment, David Grimm—online news editor for Science—talks with host Sarah Crespi as part of a live podcast event from the AAAS Annual Meeting in Austin. Sarah also interviews Science News Editor Tim Appenzeller about Neandertal art. The unexpected age of some European cave paintings is causing experts to rethink the mental capabilities of our extinct cousins. For the monthly books segment, Jen Golbeck interviews with William Glassley about his book, A Wilder Time: Notes from a Geologist at the Edge of the Greenland Ice. Listen to previous podcasts. [Image: Marcus Trienke/Flickr; Music: Jeffrey Cook]
Genes that turn off after death, and debunking the sugar conspiracy15 Feb 2018
Some of our genes come alive after we die. David Grimm—online news editor for Science—talks with Sarah Crespi about which genes are active after death and what we can learn about time of death by looking at patterns of postmortem gene expression. Sarah also interviews David Merritt Johns of Columbia University about the so-called sugar conspiracy. Historical evidence suggests, despite recent media reports, it is unlikely that “big sugar” influenced U.S. nutrition policy and led to the low-fat diet fad of the ’80s and ’90s. Listen to previous podcasts. [Image: Lauri Andler (Phantom); Music: Jeffrey Cook]
Would happy lab animals—rats, mice, even zebrafish—make for better experiments? David Grimm—online news editor for Science—talks with Sarah Crespi about the potential of treating lab animals more like us and making them more useful for science at the same time. Sarah also interviews Jon Abbatt of the University of Toronto in Canada about indoor chemistry. What is going on in the air inside buildings—how different is it from the outside? Researchers are bringing together the tools of outdoor chemistry and building sciences to understand what is happening in the air and on surfaces inside—where some of us spend 90% of our time. Listen to previous podcasts. [Image: Austin Thomason/Michigan Photography; Music: Jeffrey Cook]
David Grimm—online news editor for Science—talks with Sarah Crespi about the chance a naked mole rat could die at any one moment. Surprisingly, the probability a naked mole rat will die does not go up as it gets older. Researchers are looking at the biology of these fascinating animals for clues to their seeming lack of aging. Sarah also interviews freelancer Douglas Starr about his feature story on the Dunedin Multidisciplinary Health and Development Study—a comprehensive study of the lives of all the babies born in 1 year in a New Zealand hospital. Starr talks about the many insights that have come out of this work—including new understandings of criminality, drug addiction, and mental illness—and the research to be done in the future as the 1000-person cohort begins to enter its fifth decade. Listen to previous podcasts. [Image: Tim Evanson/Flickr/CC BY-SA 2.0; Music: Jeffrey Cook]
